Genesis documents a year-long performance during which a large piece of fabric that codifies and contains the genetic information of the film director is woven by his mother on one of the first computers of history, the Jacquard loom. In the tension between the loving gestures of a mother and the automatic movements of a mechanical loom, this art film gives form to a reflection on technical reproducibility, the materiality of data, and on the interplay between biological and computational life.